|
|
(2E,6E)-farnesyl_diphosphate <=> amorpha-4,11-diene + diphosphate
|
4.2.3.24
amorpha-4,11-diene synthase
|
–
|
|
BRENDA:
BR48696
KEGG:
R07630
MetaCyc:
RXN-8046
|
|
|
|
dihydroartemisinate_hydroperoxide + O2 + H+ <=> artemisinin + H2O
|
not assigned
|
–
|
|
MetaCyc:
RXN-8058
|
|
|
|
artemisinic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> artemisinate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-12314
|
|
|
|
(11R)-dihydroartemisinic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dihydroartemisinate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-8055
|
|
|
|
dihydroartemisinate + O2 <=> dihydroartemisinate_hydroperoxide
|
not assigned
|
–
|
|
MetaCyc:
RXN-8056
|
|
|
|
(11R)-dihydroartemisinic_aldehyde + NADP+ <=> artemisinic_aldehyde + NADPH + H+
|
1.3.1.74
2-alkenal reductase [NAD(P)+]
1.3.1.92
artemisinic aldehyde Delta11(13)-reductase
|
–
–
|
|
BRENDA:
BR50092;
BS404367
KEGG:
R10075
MetaCyc:
RXN-8053
|
|
|
|
amorpha-4,11-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinic_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
MetaCyc:
RXN-8050
|
|
|
|
artemisinic_alcohol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinic_aldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
MetaCyc:
RXN-8051
|
|
|
|
artemisinate + O2 + H+ <=> (-)-arteannuin_B + H2O
|
0.0.0.0
|
–
|
|
BRENDA:
BR53094
MetaCyc:
RXN-20257
|
|